Browsing by Author "Misir, Sema"
Now showing items 1-12 of 12
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Antioxidant Properties and Protective Effect of Turkish Propolis on t-BHP-Induced Oxidative Stress in Foreskin Fibroblast Cells
Misir, Sema; Aliyazicioglu, Yuksel; Demir, Selim; Turan, Ibrahim; Yaman, Serap Ozer; Deger, Orhan (ASSOC PHARMACEUTICAL TEACHERS INDIA, 2018)Objective: Propolis is an important bee product, rich in polyphenolic compounds. It has antitumoral, antioxidant, antimutagenic, and other useful activities. Biological activities of propolis are generally attributed to ... -
Antiproliferative and proapoptotic activity of Turkish propolis on human lung cancer cell line
Demir, Selim; Aliyazicioglu, Yuksel; Turan, Ibrahim; Misir, Sema; Mentese, Ahmet; Yaman, Serap Ozer; Akbulut, Kubra; Kilinc, Kagan; Deger, Orhan (ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD, 2016)Cancer is a heterogeneous disease, two of whose characteristic features are uncontrollable cell proliferation and insufficient apoptosis. Various studies have investigated the antiproliferative effects of propolis, a natural ... -
Cytotoxic effect of Rosa canina extract on human colon cancer cells through repression of telomerase expression
Turan, Ibrahim; Demir, Selim; Kilinc, Kagan; Yaman, Serap Ozer; Misir, Sema; Kara, Hanife; Genc, Berna; Mentese, Ahmet; Aliyazicioglu, Yuksel; Deger, Orhan (ELSEVIER SCIENCE BV, 2018)Rosa canina is a member of the genus Rosa that has long been used for medical objectives. Several studies have reported cytotoxic effects of different Rosa species, but there has been only limited investigation of the ... -
Cytotoxic Effect of Turkish Propolis on Liver, Colon, Breast, Cervix and Prostate Cancer Cell Lines
Turan, Ibrahim; Demir, Selim; Misir, Sema; Kilinc, Kagan; Mentese, Ahmet; Aliyazicioglu, Yuksel; Deger, Orhan (PHARMACOTHERAPY GROUP, 2015)Purpose: To investigate the total polyphenolic and flavonoid contents, antioxidant power and cytotoxic activity of ethanol extracts of Turkish propolis (EEP). Methods: The total polyphenolic and flavonoid contents of EEP ... -
Effect of Turkish Propolis on miRNA Expression, Cell Cycle, and Apoptosis in Human Breast Cancer (MCF-7) Cells
Misir, Sema; Aliyazicioglu, Yuksel; Demir, Selim; Turan, Ibrahim; Hepokur, Ceylan (ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD, not define)Enriched in flavonoid compounds, phenol acids, and terpene derivatives, propolis has been shown to regulate apoptosis signaling pathways and alter the expression of microRNAs (miRNAs). In the present study, it has been ... -
The effects of barnidipine on an experimental ischemia reperfusion model of spinal cord injury and comparison with methyl prednisolone
Daltaban, Iskender Samet; Misir, Sema; Turksoy, Vugar Ali; Ak, Hakan; Cakir, Ertugrul (KARE PUBL, 2019)OBJECTIVE: Increased intracellular calcium concentration plays an important role in the secondary mechanism of spinal cord injury. In the presenting experimental study, we aimed to evaluate the healing effect of barnidipine, ... -
Evaluation of the radioprotective effect of Turkish propolis on foreskin fibroblast cells
Yalcin, Can Ozgur; Aliyazicioglu, Yuksel; Demir, Selim; Turan, Ibrahim; Bahat, Zumrut; Misir, Sema; Deger, Orhan (MEDKNOW PUBLICATIONS & MEDIA PVT LTD, 2016)Aim of Study: Propolis is a resinous bee product, rich of polyphenolic compounds and flavonoids. It is known that in different geographic zones its chemical composition varies due to the different plant sources. Many ... -
The Interaction of Clarithromycin with a New Polymer-Based Nipam-Sepiolite
Hepokur, Ceylan; Misir, Sema; Kariper, Afsin (COLEGIO FARMACEUTICOS PROVINCIA DE BUENOS AIRES, 2017)In this study, poly (NIPAM/ acrylamide/maleic acid)-sepiolite (PNAMS) and poly (NIPAM/acrylamide/maleic acid) (PNAM) polymers were synthesized for using in the release of clarithromycin drug. PNAMS composite hydrogel was ... -
Morus rubra Extract Induces G(1) Cell Cycle Arrest and Apoptosis in Human Lung and Prostate Cancer Cells
Turan, Ibrahim; Demir, Selim; Kilinc, Kagan; Aliyazicioglu, Yuksel; Alver, Ahmet; Misir, Sema; Yaman, Serap Ozer; Akbulut, Kubra; Mentese, Ahmet; Deger, Orhan (ASSOC PHARMACEUTICAL TEACHERS INDIA, 2017)Objective: Cancer is one of the most deadly types of disease and evasion from apoptosis and unstoppable cell proliferation are accepted as its distinctive features. Many studies have evaluated the cytotoxic effect of ... -
Phenolic Characterisation and Antioxidant Activity of Primula vulgaris and Its Antigenotoxic Effect on Fibroblast Cells
Ozkan, Mehtap Tugce; Aliyazicioglu, Rezzan; Demir, Selim; Misir, Sema; Turan, Ibrahim; Yildirmis, Sermet; Aliyazicioglu, Yuksel (KOWSAR PUBL, 2017)Background: Primula vulgaris has been used in traditional treatment, and its biological functions are attributed to its polyphenolics content. Objectives: The aim of this study was to determine the phenolics composition ... -
Release of Doxorubicin's Active Ingredient from the Hydrogels Derived from Acrylamide and their Biological Functions
Misir, Sema; Hepokur, Ceylan; Kariper, I. Afsin (ASSOC PHARMACEUTICAL TEACHERS INDIA, 2019)Poly (HEMA/acrylamide/methyl methacrylate) (PHAM) and Poly (Acrylamide/methyl methacrylate)(PAM) polymers were synthesized for using in the release of Doxorubicin drug. Poly (HEMA/acrylamide/methyl methacrylate) (PHAM) and ... -
Selective Cytotoxic Effect of Dorycnium pentaphyllum Extract on Human Breast, Liver, and Lung Cancer Cells
Demir, Selim; Turan, Ibrahim; Misir, Sema; Aliyazicioglu, Yuksel (KAHRAMANMARAS SUTCU IMAM UNIV REKTORLUGU, 2019)Although some studies have evaluated the cytotoxic activity of different Fabaceae species, there has been only limited research into the cytotoxic effect of Dorycnium pentaphyllum. The purpose of this study was to determine ...